Identification biomakers for embodied brain by ECoG/functional MRI

Abstract

Present brain functional localization was done by electrical cortical stimulation (ECS). Although ECS is simple and easy to use clinical routine, we never know the functional dynamics, network and the gradual modulation by training or rehabilitation. Recent functional MRI provide sequential changes of brain functions and indicate multiple-foci related to higher brain functions. Furthermore, electrocorticogram (ECoG) with implanted subdural grids provides us high oscillation signals with good time-resolution directly from the brain surface. ECoG has great potentials to identify the eloquent cortices in real-time and decode brain signals related to modulated functions by any stimuli by combining support vector machine, sparse logistic regression and others. ECoG it the best tool to reveal brain functional dynamics and connectivity, Decoding brain signals would contribute to developing brain computer interface for controlling robots and communication devices. It is indispensable to make tight and continuous collaboration with researchers with different backgrounds.