2021 Volume Annual59 Issue Abstract Pages 150
In the exploratory R&D phase of mechanical circulatory support (MCS) devices, mock circulation tests are useful in reducing the cost of animal experiments. In this presentation, we will first show the mechanism by which our mock circulation system can generate fluid loads simulated different cardiac conditions, and its application to MCS devices evaluation. On the other hand, many in silico hemodynamic simulators have been reported including applications to the field of artificial organs. They are expected to be further utilized in the development of MCS devices with the recent advances in computer technology. In this report, we present the results of a basic study on the control of a ventricular assist device using a PC-based real-time biventricular hemodynamic simulator constructed with a simple electrical circuit model. We will also report on our efforts to apply the same simulation method to the improvement of a mock circulation system.