Photonic Information Technology Contributing to Medical Transducers

Abstract

In this talk, photonic information technology promising for the design of medical transducers are introduced. Light functions as a probe for observing various substances and biological activities. An arbitrary light wave distribution can be controlled to generate sub-diffraction array spots using inter-spot interference. The state of cells and tissues are detected as an optical signal via fluorescent molecules. These fluorescent molecules can be freely arranged using sequence-designed DNA, and even logical operations depending on the state can be achieved. Forster resonance energy transfer enables to generate various response characteristics with several kinds of fluorescent molecules. The imaging system TOMBO, inspired by the compound eyes of insects, can be used to capture such optical signals effectively. By integrating optical systems with different properties, 3D shape measurement, multispectral imaging, etc. can be performed. Furthermore, various imaging modalities are achieved by signal processing such as compressed sensing and machine learning.