抄録
Recent advances in muscle physiology were briefly reviewed in respects of subcellular structure of skeletal muscle fibre, excitation-contraction coupling, effect of electrical field stimulation, contractile mechanism and dynamics of muscular contraction.
Discovery of the transverse tubular system (T-system) and the elucidation of the role of calcium ion bound by the sarcoplasmic reticulum in the initiation of contractile reactions suggested that the ion may connect the excitation in the surface membrane to the contraction, and that the stimulation of the coupling site directly by electrical current may produce the contraction.
The sliding-filament theory in sarcomere was proposed on the basis of the observation of myofilament by electron microscope and some intimate physiological evidences. Ih the dynamics of muscular contraction, however, the series elastic component and the characteristic system for energy mobilization complicate the relations among muscle length, tension and shortening velocity.