D-1 CHITOSAN-CALCIUM PHOSPHATE CEMENT COMPOSITES FOR BONE SUBSTITUTES(Session: Biomaterials)

抄録

Calcium phosphate cements were prepared by mixing many calcium phosphate combinations, aqueous solutions of chitosan and studied the effect of the concentration of chitosan on the mechanical strength and setting behavior of cements. Compressive strength and setting time of samples were determined. 5%wt chitosan in acetic acid with cement compositions gave higher the mechanical strength and faster the setting time of cements than aqueous solution. The formation of hydroxyapatite was found in the cements after curing in 100% humidity at 37℃ for a week.