Currently, Alzheimer's treatment and medication is become to popularity topic in the world. Scientist and Researchers are looking for new treatments to alter the course of the disease and improve the quality of life for a person who was with Alzheimer's disease (AD). The potential of Low level light therapy (LLLT) has a lot of benefits in the areas of physical medicine and rehabilitation. In this studies bring the basic knowledge between optics and cell culture. Neuron cells were mimicked liked Alzheimer's disease by using P-amyloid solution Then, Alzheimer's cell were treated by light emitting diode (LED)-called phototherapy at 630 nm for proving in the cellular level that light from LED can inhibited P-amyloid peptides.