抄録
Magnetic fluid is the material that the magnetic fine particles is dispersed uniformly by a dispersant in solvent. In this study, we designed and manufactured the magnetic fluid which has a biocompatibility and a superior magnetic characteristic by using the PEGylated polyacrylic acid (PAA) as a new dispersant instead of the chondroitin sulfate C which we used before. Furthermore, we evaluate influences on characteristics such as the mean colloidal diameter, the magnetic characteristic, mean diameter of the magnetic fine particles and the composition of magnetic fluid by the PEGylation. First, Fourier Transform Infrared Spectrophotometer was used to confirm the bond of PEGylated PAA. As a result, it was confirmed the PAA was PEGylated. Next, the mean colloidal diameters were investigated by using Dynamic Light Scatting. This experience yields that mean colloidal diameter tend to increase by PEGylation. Also, to investigate the magnetic characteristic, the magnetization curves were acquired by using Vibrating Sample Magnetometer. So that, it was recognized that magnetic characteristic decreased by increasing ratios of compounded PEG. In addition, the composition of magnetic fine particles was analyzed by using X-Ray Diffractometer. And the magnetic body of the γ-Fe_2O_3 was recognized as a core like the magnetic fluid using the chondroitin sulfate C. Furthermore, magnetic fine particles were photographed by Transmission Electron Microscope and the mean core particle diameters were measured from the image. As a result, composition of the PEGylation didn't influence the core particle diameters.
