This paper presents the sensitivity analysis of multi-body dynamics (MBD) model for automobile suspension systems, where the geometry of joint as well as mass, stiffness and damping coefficients are design parameters. By this method, we can ascertain which elements contribute for the dynamic characteristics of the system. This paper mainly focuses on the effectiveness and advantages of sensitivity analysis. The effectiveness of the sensitivity analysis for MBD system is verified by comparing with the response surface approach. The optimization of dynamic properties of the suspension system based on the sensitivity analysis is also examined.