Abstract
We have successfully produced emulsion droplets on a chip both achieved size-control and on-demand droplet generation by using magnetically driven microtool (MMT) which has a parallel plate structure to be constrained in translational motion. With a lateral motion of MMT in microchannels, the dispersed phase (hydrophobic flow) can be cut into different size of droplets and the continuous phase (hydrophilic flow) flow can be flowed into the microchannels by the movement of MMT to obtain both of size-controlled droplets and on-demand droplets actively. The improved system was evaluated in terms of the frequency oMMT and the size of droplets produced, and we found out a dynamic range of the size control of droplet was improved. In this paper, we propose to improve the size of droplet with a microsensor fabricated on substrate by photolithography, which provides closed-loop size control of production of droplet by MMT. Our target is to stabilize the system. This system contributes to emulsification process for biotechnology and nano-medicine applications.
