We have developed a new artificial pancreas system, "BIONIC artificial pancreas". This was consisted of two types existing artificial pancreas, which were open-loop mechanical artificial pancreas and hybrid artificial pancreas. By combining these two types of artificial pancreas, several problems of both were complemented. In the present study, we developed the simulation software about the blood control system from our experimental data, and investigated the Usefulness of this new system with this software and an animal experiments.
