The Proceedings of Mechanical Engineering Congress, Japan
Online ISSN : 2424-2667
ISSN-L : 2424-2667
2012
Session ID : BC-JP-1
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BC-JP-1 Development of Multiscale Thrombus Simulator
Shu TakagiSatoshi IiSeiji ShiozakiNorio ShimamotoKazuyasu SugiyamaYoichiro Matsumoto
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Abstract
We have been working on the development of a full Eulerian formulation method for solving fluid-structure interaction problems.The original method [1] has been extended for fluid-membrane interaction problems [2].This method is applied to the blood flows containing red blood cells and platelets.Then,it is further extended to multiscale thrombosis simulation,which couples Monte-Carlo simulations for the molecular scale protein-protein interactions with continuum scale simulations.These simulators are developed for the massively parallel computation.The results reveal that the flow fluctuation given by the presence of red blood cells plays an important role to make the platelets adhering on the vessel wall.
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© 2012 The Japan Society of Mechanical Engineers
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