Abstract
Tiny bubbles in liquid have wide variety of applications. They can be effectively used to purify the water or to enhance the gas-liquid chemical reactions. Microbubbles are also used as contrast agents for ultrasound diagnosis. And they are now expected to be used for the therapy. In the case of therapy, there are several ways to use microbubbles with high intensity focused ultrasound (HIFU), such as cauterizing cancers, drug delivery, gene transfection etc. For these types of applications, the microbubbles need to have some special treatment on their surface, such as surface coating or modifications with lipid molecules, ligand proteins etc. Aiming at the wide variety of the medical applications of microbubbles with ultrasound field, we are developing the methods to give many functions to microbubbles. In the present talk, microbubble generation using T-junction microchannel and vesicles break-up using microbubbles are discussed.
