抄録
The cardiac hemodynamics is of great importance in determining the condition of the whole human circulatory system. However, the flow patterns in heart are always complex and difficult to be fully depicted by medical measurements, which calls for a reasonable numerical simulation method capable of investigating the cardiac hemodynamics in quantitative terms. To this end, we developed a multi-scale computational method by means of coupling a closed-loop lumped 0D model for the human cardiovascular system with the 3D computation of the hemodynamics in the left ventricle. The predicted results are in satisfactory agreement with the previous data where available. Moreover, owing to its multi-scale property, the present method favors a flexible analysis of the cardiac hemodynamics under various conditions either normal or pathological.
