The cloning is one of the most promising biotechnologies today. The project aims to automate every process required in the cloning, i.e. cutting, removing, filtering, assembling and fusing, on the basis of micro RT. The processes are performed on a micro chip consisting of micro channels and chambers in which egg cells and membranes flow and are manipulated. A whole system would be small and compact enough to be fit on desk top to meet various demands in biotechnology. The objectives, the overview and the current progress will be introduced in this keynote.