多光子リソグラフィによって作製されたマイクロサイズ人工細胞骨格によるリポソーム変形

抄録

We created the non-spherical liposomes with artificial micro-cytoskeleton. First, we fabricated micro-cubic frames with 3D-laser-printed photoresists. Next, we formed water-oil-water interface on the faces of these microstructures in a microfluidic channel. Finally, we confirmed whether this interface was lipid bilayer membrane by using α-hemolysin as a membrane protein. As a result, we successfully observed the solution encapsulated by lipid bilayer membrane formed around the microstructures.