2P1-A28 On-chip Nuclear Transfer : Part 3: Proposal of Cell Coupling Method Using Magnetically Driven Microtool

Abstract

This paper presents a novel method of cell coupling on a chip by using magnetically driven microtool (MMT). This MMT was made of Nickel and it is also has a function as electrode. The novelty of the chip is the electrode itself can be moved by external magnetic field using a spring structure. We proposed a new cell coupling chip which provides larger coupling force of cells by using a physical force by MMT in addition to the dielectrophoretic force. FEM analysis and an experiment confirmed its operation on a chip by external magnetic force. This chip contributes to the high throughput cell manipulation as well as electrical measurement.