1A2-D06 Femtosecond Laser and Mask Hybrid Exposure (FMEx) : Fabrication of Circulation Type 3D Capillary Vessel Simulator(Nano/Micro Bio System)

Abstract

We have been developed circulation type blood vessel simulators simulating arteriole network. These simulators have circular cross sections and are achieved by seamless connecting arteriole models and artery models. However, these models have two-point-five-dimension (2.5D), we needed to fabricate three-dimensional (3D) blood vessel simulators for simulating real blood vessel structures with a high degree of accuracy. For this purpose, we propose a novel 3D exposure method as femtosecond laser and mask hybrid exposure: FMEx. FMEx is integrated two-photon absorption exposure by femtosecond laser and conventional photolithography by mask aligner. We report the results of prototyping the circulation type 3D capillary vessel simulator by using FMEx.