1A1-D11 Modeling and Optical Control of BioActuator using Transgenic Muscle Tissue : Photoresponsive evaluation of Transgenic Somatic Muscle of Drosophila Melanogaster(Bio Manipulation)

Abstract

The purpose of this study was the fabrication of Bioactuator using transgenic somatic muscle and the evaluation of the light response characteristics of the Bioactuator. Transgenic somatic (body-wall) muscle of the larva of Drosophila Melanogaster fruit fly was used as a Bioactuator. In this report, we first made photosensitive somatic muscle, which express channelrhodopshin-2 (ChR2) with gene manipulation. Then, we made a comparative review of some methods of utilizing the ChR2 expressing somatic muscle as a Bioactuator to generate contractile force in the one-dimensional direction. Finally, we confirmed the step response of the Bioactuator to optical stimulation in order to evaluate its basic characteristics.