抄録
This paper presents fundamental evaluation of needle-free bubble injector which has been developed recently. The needle-free bubble injector is mainly composed of an inner glass electrode surrounded by outer reagent-supply shell. Cavitation of a single bubble occurs at the tip of inner electrode and perforates biological tissue immediately when the voltage is applied to the electrode. Subsequently, the bubble is launched at high speed from the electrode transporting reagent into the biological tissue. This device can be used under liquid as well as under air environment. This novel device is applicable to various typs of cells such as animal cell or plant cell with minimally invasiveness. This method will contribute to wide range of biological applications such as gene therapy and gene transformations.
