脈流生成システムを応用した複雑管状構造の構築

抄録

In recent years, research targets in tissue engineering have been shifting from simple tissues such as muscle and skin to more complex tissues like living organs. Among living tissues, there are many types of tubular structures in vivo such as blood vessels, tracheas and intestine. These tubular structures have multiple-layered and wavelike surface in order to absorb nutrients or secrete hormones and other material efficiently, so we need to construct these complex tubular structures to reproduce their various functions. In this paper, we propose a novel device which integrates a pulsatile flow generating mechanism and a tubular structure generating device in order to construct complex tubular structures with wavelike surface like living tissues.