単一ナノ粒子の光干渉検出

抄録

A nanoparticle flow cytometer that can detect particles of the order of 10 nm by combining the heterodyne interferometry and the lock-in detection has been developed. Employment of a beam expander and an objective lens with greater magnification than our previous report can contribute to enhance the resulting S/N ratio by the factor of six and to improve the detection limit of the system from 200 nm to 20 nm (gold particles). Moreover, detections of particles made of different material were performed.