2023 Volume 3 Issue 1 Pages 20-30
< Introduction> Ordinary Alzheimer’s disease (AD) has recent memory disturbance as initial symptom, which is often accompanied by general deterioration in judgment and executive dysfunction, and cortical symptoms such as aphasia and apraxia. However, there are subtypes of AD with language symptoms as the main symptom, Matsuda, et al. 1) Logopenic primary progressive aphasia, 2) Difficulty wording/kanji amnesic agraphia →transcortical sensory aphasia, 3) Left temporal lobe type (semantic dementia (SD)like AD). This time, we also experienced 1) 3 cases, 2) 1 case, and 3) 6 cases in in these 3 types, so we will present representative cases and report on the diversity of language symptoms of AD.
<Methods> In addition to examininig the clinical symptoms of each case by interview, we also examined neurological symptoms, MRI, SPECT, neuropsychological tests (HDS-R, MMSE), and SLTA.
<Results> The age at onset was 70 years or older. It was difficult to differentiate AD from SD, because all cases were not underwent SPECT and SLTA.
<Conclusions> Language functional evaluation is important to understand the original cognitive functions of AD, and understanding the language symptoms of AD is also useful for differential diagnosis from other diseases.
