2016 Volume 69 Issue 4 Pages 163-171
The aim of this study was to clarify differences in subjective appetite and gastric motility after ingestion of a solution of either a noncaloric artificial sweetener, sucralose (SR) , or sucrose (S) . Twelve young women began fasting at 10:00 pm on the previous night, then ingested SR and S, or plain water (W) as control, at equivalent temperature, volume (15℃, 150 mL) and sweetness at 9:00 am on different days. The subjects were administered the separate sweet samples (30 mL) orally and instructed to swallow after sufficient mixing in the mouth, which was repeated 5 times. For evaluation of sweet taste, the scores before ingestion, and during ingestion of the 1st and 5th cups of the sample were used. Electrogastrograms, electrocardiograms (heart rate) , and body temperatures were obtained 20 min before and 65 min after sample ingestion. Subjective appetite was evaluated before and every 15 min after ingestion. Both of the sweet-tasting samples, but especially SR, suppressed hunger immediately after ingestion, and postprandial subjective appetite increased according to the perceived sweetness (S and SR) . Differences in electrogastrogram responses were found after ingestion of S and SR; elevated HR was observed only after ingestion of S. Our results suggest that SR increases neither heart rate nor body temperature, but temporarily suppresses subjective appetite and alters gastric motility in comparison with S.
