2021 Volume 74 Issue 1 Pages 15-20
The present study investigated the inhibitory effect of bread containing powdered Morus australis leaves on postprandial elevation of the blood glucose level. First, we assessed the 1-deoxynojirimycin (1-DNJ) content and α-amylase- and maltase-inhibitory activities of bread containing powdered M. australis leaves. Second, we investigated the inhibitory effect of this bread on blood glucose elevation in healthy individuals. Although the level of 1-DNJ was reduced during the bread-making process, 1-DNJ was still present in the bread containing powdered M. australis leaves. The powdered leaves exhibited no α-amylase-inhibitory activity. Although the median maltase-inhibitory concentration was higher in the bread containing the powdered leaves than in the powdered leaves alone, this bread retained its maltase-inhibitory activity. Moreover, consumption of the bread containing powdered M. australis leaves suppressed postprandial elevation of the blood glucose and insulin levels to a greater degree than consumption of bread without the powdered leaves. These findings demonstrate that bread containing powdered M. australis leaves has an inhibitory effect on postprandial blood glucose elevation.
