Molecular Nutritional Study on Healing and Prevention of Pressure Injury

(JSNFS Award for Young Investigators (2023))

Abstract

Protein malnutrition is largely associated with delay or failure of the healing process in elderly people and hospitalized patients. However, the effect of dietary protein quality on wound healing is largely unknown. This study investigated the effect of dietary protein quality on wound healing and attempted to clarify the regulatory mechanisms responsible in model rats with full-thickness cutaneous wounds. The study findings suggested that low-quality protein diets might have negative effects on wound healing by decreasing collagen deposition in rats.