Abstract
To examine the influence of excess lysine on glutamic -pyruvic transaminase (GPT) and glutamic-oxalacetic transaminase (GOT) activities in serum and liver and on the excretion of urinary amino acids, young rats were fed with 4, 8 or 16% casein diets supplemented with 4% L-lysine HCl for 14 days.
The growth of rats, feed efficiency ratio and nitrogen efficiency ratio in each groups were decreased by the supplement of lysine. Serum and liver GOT activity was not changed and GPT activity increased by the supplement of lysine. The amount of urinary excretion of total nitrogen, lysine, a-aminoadipic acid and glutamic acid were strikingly increased by the excess lysine.
