Abstract
Toxic symptoms caused by the putrid Matsutake mushrooms were quite similar to those by the reference amines.
The lethal quantity of phenylethylamine alone was MLD 264mg/kg. However, once mixed with 285mg/kg of histamine, 85mg/kg of phenylethylamine was already lethal.
A MLD curve was drawn on the varying rate of histamine and phenylethylamine. The MLD of the putrid Matsutake mushrooms came very close to it.
Histamine and phenylethylamine appearing in the early stage of putrefaction seemed to work multitudiously cause toxic symptoms on rats closely similar to those by allergic food poisoning.
