Abstract
Smith claims in 1942 that the creatinuria of women is exaggerated during premenstrual period, but he did not take the effect of diets into consideration. The authors reexamined the relation between the excretion of creatine and the periods of menstrual cycle with three women, who continued to take the same diets, throughout the experimental period.
The daily variation of the excretion of creatine has been so considerable that a definite relation between the creatinuria and the period during the menstrual cycle could not be found.
Contrary to expectation, the urinary estrogen also had not a constant relation with the menstrual cycle.
