Abstract
The serum cholesterol levels were measured in the rats fed with 5% casein diets supplemented with amino acid mixtures, each lacking lysine, isoleucine, arginine, cystine-methionine and aspartic acid. The results showed that arginine and aspartic acid had no cholesterol lowering effect, although lysine and isoleucine seemed to have a contribution in the lowering effect.
The lowering effect was connected closely with amino acid balance which defines the quality of the dietary protein. An administration of dietary protein containing sufficient and well-balanced amino acids may reduce the amount of serum cholesterol.
