Abstract
In a previous paper* the authors showed that the inclusion of dried mushrooms in the rat diet was an effective means of lowering blood plasma cholesterol. In order to determine the nature of the substance responsible for this effect, mushrooms were extracted successively with ether, water and ethanol.
The results showed that the ether-soluble fraction was ineffective, and that the water-soluble fraction effectively lowered plasma cholesterol. The ethanol extracts contained only slight and variable activity in accord with the previous extraction of the activity with water.