Abstract
The effects of a planned body weight reducing regimen on the serum free fatty acid level in 36 obese women and on the glucose and free fatty acid responses to oral glucose tolerance test in another 36 obese women were investigated.
The subjects were divided each into 3 groups, Low Obese (average body weight -120%), Moderately Obese (120-140%) and Grossly Obese (140%-). The treatment period was 15 weeks and an average weight loss was 6.2kg or 12.2% of initial body weight.
Before the regimen, fasting levels of serum free fatty acid were found no differences among 3 groups, and after the regimen a significant fall in fasting levels were not observed.
Before the regimen, obese groups had significantly higher glucose and free fatty acid levels in blood as the responses to 50g oral glucose tolerance test than did the Low Obese group. After the regimen, these responses were not improved, instead rather aggravated, and the mechanism of this phenomenon was discussed.
