Abstract
The effects of excess sodium chloride intake on the iodine metabolism in rats were studied changing the ratio of sodium chloride to iodine.
Abnormal symptoms in the growth and thyroidal weights were not observed by the administration of more than 2μg of iodine per rat per day, even when 2.5% sodium chloride diets were given. However when excess sodium chloride was given, enlargement of kidneys was observed comparing with controls.
Also in the groups given the small amount of iodine, iodine excretions in urines, the iodinecreatinine ratio and thyroidal iodine contents decreased by the excess sodium chloride intake.
The cholesterol and phosphorus contents in serum were not affected by the excess sodium chloride intake.
