Abstract
The mechanism of photodynamic action of the salted takana or pheophorbide a isolated from the salted takana on erythrocyte of rats was investigated in vivo and in vitro. The following results were obtained.
After rats fed 10% salted takana diet for 2 days were exposed to visible light, all the animals died within 5.5 hours. On rats fed with 5% salted takana diet and exposed to visible light for 10 hours, it was recognized that erythrocyte was decreased as well as in hematocrit value.
Pheophorbide a caused hemolysis of blood suspension with the exposure of visible light but not without the exposure. Its hemolytic ability was reduced by the pre-treatment with visible light.
