Abstract
The effect of polymetaphosphate (PMP) on the absorption of calcium was estimated from theincrement of serum calcium and phosphorus level.
After 15hrs of fasting, each rabbits were given 250mg of calcium chloride with 25, 50 or 100mg of PMP per 1kg of body weight. Calcium chloride and PMP were dissolved in water, and given through a stomach tube. Change of serum calcium and phosphorus levels was examined at some time intervals.
The increase of the calcium level in serum was suppressed with administration of 50 or 100mg of PMP and phosphorus value in serum decreased slowly during the experimental period.
But in the administration of 25mg of PMP, the calcium value in serum increased from 4.1 to 12.3% during 1hr of the experimental period, therafter the value was restored to the initial level.
After 15min of administration of 25mg of PMP, the phosphorus value in serum increased temporalily, but then the value decreased rapidly in the following 1 and 2hrs and therafter the value appeared to be restored.
From these results, it was assumed that calcium absorption was suppressed with 50 or 100mg of PMP, but 25mg of PMP did not have a pronounced effect on the calcium absorption.
