Nippon Eiyo Shokuryo Gakkaishi
Online ISSN : 1883-2849
Print ISSN : 0287-3516
ISSN-L : 0287-3516
Effect of Extracts from Hovenia dulcis Thunb. on Alcohol Concentration in Rats and Men Administered Alcohol
Yutaka OKUMAHisashi ISHIKAWAYosio ITOYoshioki HAYASHIAkira ENDOTokinori WATANABE
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1995 Volume 48 Issue 3 Pages 167-172

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Abstract

The effect of extracts from Hovenia dulcis Thunb. on alcohol (ethanol) concentration after administration of alcohol to rats and men were examined. When a fraction (Fr. G, 0.5g/kg b. w.) extracted from H. dulcis was administered orally to rats 5min before oral administration of alcohol (2g/kg b. w.), the percentage decreases in maximum blood alcohol and acetaldehyde levels were 40% and 37%, respectively, the decreases being larger than those induced by other fractions from H. dulcis. On the other hand, when ethanol extract (0.125g/kg b. w.) was administered orally to men 20min before oral administration of alcohol (0.3g/kg b. w.), decreases in alcohol and acetaldehyde concentrations in saliva were observed, and the expiratory alcohol concentration at 1h after drinking beer was significantly decreased in five men out of eight

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