Abstract
We prepared a mixture (SK-204, 10% in diet) consisting of dried shiitake mushroom (Lentinus edodes) treated by wet-heating and fructo-oligosaccharides (7: 3), and evaluated its action on lipid levels in rats fed a cholesterol diet for 14 days. Administration of SK-204 suppressed the increases of cholesterol and phospholipid levels in the serum, and those of total lipid, cholesterol, triglyceride and phospholipid levels in the liver. These results suggest that SK-204 can suppress the increase of lipid contents in the blood and the accumulation of lipids in the liver resulting from ingestion of cholesterol.
