Abstract
In the present study, we prepared chondroitin sulfate and its oligosaccharide mixture from the nasal cartilage of the salmon, and investigated the effects of these samples on intestinal absorption of glucose. The samples were found to inhibit glucose uptake in brush border membrane vesicles prepared from rat jejurum. These results suggest that chondroitin sulfate from salmon nasal cartilage may improve pathological states of obesity by inhibiting the intestinal absorption of glucose derived from dietary carbohydrate.
