神経変性疾患の栄養療法の基礎

抄録

Nutritional therapy for neurodegenerative diseases is described, using amyotrophic lateral sclerosis (ALS) as an example. Several clinical trials are underway to test whether the prevention of body weight loss can improve outcomes. A formula for predicting the appropriate caloric requirement in ALS is also reported. In addition, three approaches to managing the nutrition of patients with ALS need to be considered : increasing the number of calories consumed, using tools to support the diet and nursing. During the advanced stages of the disease, it is important to monitor respiratory function frequently and to avoid missing the timing of percutaneous gastrostomy.