マラソンレクチャー
抗ミエリンオリゴデンドロサイト糖タンパク質抗体関連疾患の病態と治療
キーワード:
myelin oligodendrocyte glycoprotein (MOG),
anti–MOG antibody,
MOG–IgG associated disorders (MOGAD)
2022 年 39 巻 3 号 p. 183-185
詳細
2022 年 39 巻 3 号 p. 183-185
MOG–IgG associated disorders (MOGAD) is a central nervous system disorder caused by anti–MOG antibodies and is diagnosed by cell–based assays to detect anti–MOG antibodies. The diagnosis of MOGAD is important to differentiate it from MS and NMOSD. The age of onset of MOGAD has two peaks, in childhood and in the 30s, and there is no sex difference in the number of patients. Symptoms include frequent optic neuritis, often accompanied by ocular pain. Treatment is successful with pulsed steroid therapy, but about half of patients relapse without treatment.
