2023 年 40 巻 5 号 p. 698-701
Recent advances and new findings relating to multiple sclerosis (MS) and other inflammatory disorders in the central nervous system including neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein–associated disease (MOGAD) were reviewed. The following topics were discussed : the association between Epstein–Barr virus infection and MS development, the relevance of serum neurofilament light chain measurement in MS, the association between brain atrophy and progression independent of relapse activity in MS, the efficacy and safety of extended interval dosing of natalizumab for MS, the initial immune mechanism in NMOSD, the decrease of retinal vessels in NMOSD, the neuroaxonal damage and astrocytic injury in MOGAD, and the effectiveness of maintenance intravenous immunoglobulin for MOGAD.
