3回目の診療ガイドライン（改訂）からみる筋萎縮性側索硬化症ケアの現在地

抄録

In Japan, the ALS guidelines are revised approximately every 10 years, with new guidelines published in 2002, 2013, and now 2023. Although the cause of ALS remains unclear and the treatment method has not yet been established, the “landscape” of ALS care has changed considerably in the past 20 years.

The publication of two Clinical Questions (CQs) for the first time was a milestone, but does not encapsulate the entirety of ALS care. With the extremely limited number of items for which the total body of evidence from systematic reviews could be evaluated, many were combined into Questions and Answers (Q&A) to collate clinical knowledge. The author participated in this process as a non–physician member of the committee and learned a great deal. The discussions in the working groups and panel meetings were, to put it colloquially, an all–Japan multidisciplinary team.

In this article, I would like to introduce the current state of ALS care, tracing the transition of the chapters in the past three guidelines, and share the changes in the “view” of ALS care over the past 20 years.