Salivary gland tumors derived from minor salivary glands are relatively rare, but it is often difficult to distinguish between benign or malignant. Also, in the case of malignant tumor, treatment methods other than surgical resection are not established and it is often difficult to take measures. We report three cases of malignant salivary gland tumor that was thought to be derived from minor salivary glands clinically. The cases included a man and two women ranging in age from 32 to 65 years old; two patients had it on the retromolar site, and the other had it on the buccal mucosa. Histopathological diagnosis included two patients with mucoepidermoid carcinoma and the other with adenoid cystic carcinoma. In two cases, chemotherapy and radiotherapy were conducted as additional treatments after surgery. Subsequently, one case resulted in relapse or metastasis.
