We report a case of spindle cell lipoma （SCL） which developed in the right buccal mucosa. The patient was a 54-year-old woman with the chief complaint of a mass in the right buccal mucosa. At the first visit to our clinic a pedunculated and well-circumscribed mass, measuring 15×20mm, was observed in the right buccal mucosa. Magnetic resonance imaging （MRI） showed a well-circumscribed lesion with low signal in the T1 weighted images, high signal in the T2 weighted images, and slightly high signal in the STIR images. Based on the clinical and imaging findings, we diagnosed the lesion as a pedunculated benign tumor and excisional biopsy was performed under local anesthesia. The surgical specimen was pathologically and immunohistochemically diagnosed as spindle cell lipoma （SCL）. No symptoms of recurrence have been recognized for 3 years after surgery.
