2003 年 16 巻 4 号 p. 493-506
We applied atelocollagen sponge into the wounds of tooth extraction of 40 compromised patients and compared the results with those of 26 healthy patients. The degree of hemostasis, pain, infection and wound closing time were compared. The compromised patients were a diabetic patient, dialysis patient, hepatic diseased patient, patient on oral anti-coagulation therapy such as warfarin or hepar in for circulatory disorders, and cerebrovascular diseased patient. It is known that these compromised patients are prone to bleeding, infection and delayed wound healing.
Atelocollagen sponge indicated high hemostasis, high alleviation of pain, infection control and the wounds closed at 1.72±1.45 weeks in healthy patients. Although hemostasis was slightly inferior to that of healthy patients, the alleviation of pain and infection control were equal to those of healthy patients, and the wounds closed at 1.34±0.52 weeks (T-test;p=0.22) in compromised patients. There were no side effects in both patients.
As a result, we consider that atelocollagen sponge is not only a good material for the wounds of tooth extraction in healthy patients, but is also useful for compromised patients.