抄録
In this work, the authors investigated the process of bone regeneration with the aid of woven cloth made of bioactive glass fibers, BGF-1. Bone defects made in the tibial bones of Wistar rats were covered either with BGF-1 glass cloth or industrial E-glass cloth for 2 to 3 weeks, and then histological observations were made. As for the results, bone formation was recognized in the bone defects covered with the BGF-1 glass cloth, while it was not recognized in the defects covered with the Eglass cloth. From the results of the implantation of the fibers into the hypodermal tissue, BGF-1 fibers were considered to be slowly resorbed in the living body since the fibers were subjected to phagocytosis by giant cells. BGF-1 fibers were shown to be capable of ion exchange with oxonium ions to give off sodium and calcium ions, which is an essential characteristic for bioactive glass. From the E-glass cloth, on the other hand, the extent of the ion exchange was very small. The controlled release of sodium and calcium ions from BGF-1 was considered to be sufficient for the emergence of bioactivity.
