2019 Volume 32 Issue 3 Pages 210-216
Various stem cell-based therapies and regenerative medicine have started clinical trials. Nevertheless, such applications are still rare in dental practice. The complexity and issues of cell culture systems, such as huge cost, devices, laborious works, and time hamper the advancement of cell-based therapies. This paper reviews the infrastructure of cell culture systems and related issues. Additionally, we have recently developed novel bone regenerative materials using a botanical-based substance (catechin isolated from green tea) and aqueous chemical synthesis. The materials have advantages in terms of cost and environmental issues. We also introduce the function of fabricated epigallocatechin gallate-modified gelatin sponge for bone regenerative medicine.
