Journal of Japanese Society of Oral Implantology
Online ISSN : 2187-9117
Print ISSN : 0914-6695
ISSN-L : 0914-6695
Histological Study of Bone Formation by Partialy Purified BMP in Dog Mandibular Bone Cavity
Yumiko FukunishiNaruyoshi AbeKenji IinoKatsuhiko IwanagaShigeki TanakaHiroshi SekineAkira MishimaKeisuke NakanoChofuku HohBing-Zhen HuangMasaru Murata
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1996 Volume 9 Issue 2 Pages 313-320

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Abstract

The purpose of this study was to promote bone formation in the bone cavity after insertion of two kinds of partially perified bone morphogenetic protein (BMP). After insertion in the dog mandible, materials evaluated by histological study at 1, 3, and 5 weeks. G-Ext level BMP (G-Ext BMP) alone and Heparin level BMP-Insoluble bone matrixcomposites (SMP-IBM) produced new bone rapidly. G-Ext BMP and Heparin BMP quickly induced differentiation of the mesenchymal cells into osteoblastic cells in bone cavity of the dog mandible.

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© 1996 Japanese Society of Oral Implantology
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