Abstract
Oral dose of 200 mg Sparfloxacin was administered before exodontia in 206 patients. The drug concentration of Sparfloxacin in the blood from the exodontia wound was measured.
80 % of MIC isolates from odontogenic infection including Oral Streptococci was 0.39 μg/ml.
This antimicrobial agent is valued≥0.39 μg/ml in 95 cases out of 126 cases (75 %) from 135 minutes to 300 minutes after peroral administration.
