Abstract
Loxoprofen sodium (Loxonin®) is one of the anti-inflammatory analgesics of the phenylpropionic acid group. Its side effects on digestive organs are less than those of other analgesics because of prodrug. In thes study, for 50 cases with postexodontic pain, the analgesic effect and safety of Loxonin® were clinically evaluated after impacted wisdom tooth extraction.
1. The frequency of the analgesic effect was 82 % according to impressions of patients, and 80 % by the judgment of the doctor.
2. Nobody knew the side effects of the drug.
3. The frequency of the reduction of a pain was 76 %, and the duration of effect was 84 %, each those rates were over “effective”.
From the results of this study, it was suggested that Loxonin® is effective and safe for treatment of postexodontic pain.
