抄録
There have been few reports on the effects of interdental brush with toothpaste on periodontitis. Therefore, the purpose of this study was to evaluate the effects of interdental brush with toothpaste containing cetylpyridinium chloride (CPC) on adult periodontitis with the deep periodontal pocket. Twenty patients (experimental group: 10 subjects, control group: 10 subjects) who had not received general and/or local antibiotics prior to this study were selected. They had at least 1 tooth with over 5 mm of probing pocket depth on the mesial or distal side of maxillar or mandibular incisors and first premolars without a prosthesis, and they had not undergone professional periodontal treatment. The experimental group was instructed to use a toothbrush and an interdental brush with commercial toothpaste containing 0.05 % CPC, and the control group was instructed to use a toothbrush with toothpaste and an interdental brush without toothpaste. The amount of gingival cervical fluid (GCF), ratio of subgingival microflora, probing depth (PD), clinical attachment level (AL), and plaque score for adjacent teeth (P1S) were measured at baseline, and after 2 and 4 weeks. There were no statistical differences in PD, AL, GCF, and P1S between the experimental and control groups at any period. In bacterial study, both groups did not show significant change at any time. The results suggested that CPC does not infiltrate into the bottom of a deep periodontal pocket and does not have pharmacological effects. Thus further investigation of the method of administering CPC to the deep periodontal pocket should be conducted.
